Significance of hepatic enzymes: A review

The assay of serum enzymes is very useful for the differential diagnosis and monitoring various hepatobiliary disorders. Aspartate aminotransferases are found in liver, cardiac muscle, skeletal kidneys, brain, pancreas, lungs, leukocytes, erythrocytes decreasing order concentration. Alanine muscle (cardiac skeletal), these specific indicators hepatocellular injury dogs cats not large animals pigs due to low activity liver tissue. Alkaline phosphatases markers cholestasis, present most tissues but particularly high concentration osteoblasts bone cells tract, intestinal wall, renal tubules, placenta. Gamma-glutamyl transferase occurs mainly prostate. Alcoholism damage infectious hepatitis causes elevated plasma GGT activity. Sorbitol dehydrogenase predominantly kidney measurement SDH has been shown be valuable assessing domestic species. Elevated arginase levels have observed naturally occurring diseases horses, cattle, sheep, goats, dogs. Ornithine carbamoyltransferase (OCT) primarily regarded as a liver-specific enzyme detecting necrosis This review aims highlight importance hepatic purposes.